甲型肝炎
在PubMed上查看摘要
概括
此摘要是机器生成的。型肝炎病毒 (HCV) 影响全球数百万人, 诊断和治疗有限, 阻碍了消除病毒的努力. 扩大对诊断和治疗方法的准入对于实现世卫组织2030年目标至关重要.
科学领域
- 肝病学
- 传染性疾病
- 公共卫生
背景情况
- 型肝炎病毒 (HCV) 感染是全球严重的健康问题,大约有7100万人长期感染.
- 主要通过皮肤接触血液传播HCV,高风险群体包括注射毒品的人,与男性发生性关系的男性和囚犯.
- 慢性HCV感染可能在20-30年内导致肝硬化,肝衰竭和肝细胞癌等严重并发症.
研究的目的
- 突出全球肝炎病毒感染的负担.
- 强调HCV的诊断和治疗的差距.
- 强调可访问的诊断和泛型直接作用的抗病毒治疗对消除HCV的重要性.
主要方法
- 全球HCV发病率和流行率的流行病学数据分析.
- 对HCV传播途径和高风险人群的审查.
- 评估目前的HCV诊断率和治疗率.
主要成果
- 在2015年,全球HCV发病率为每10万人口中的23.7,新感染人数为175万.
- 全球最常见的HCV基因型为1,3和4.
- 只有20%的型肝炎患者知道自己的诊断,只有15%的患者接受治疗.
结论
- 尽管有治疗性直接作用的抗病毒疗法,但诊断和治疗仍然存在重大障碍.
- 实现世界卫生组织2030年消除HCV的目标需要增加诊断和与护理的联系.
- 普遍获得负担得起的临床诊断和泛型抗病毒疗法对于消除HCV至关重要.
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