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Updated: Jan 3, 2026

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells

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瘤微环境的差异 指示 T 助手血统 两极化和对免疫检查点治疗的反应

Shiping Jiao1, Sumit K Subudhi2, Ana Aparicio2

  • 1Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center UTHealth, Houston, TX 77030, USA.

Cell
|November 16, 2019
PubMed
概括

免疫检查点治疗 (ICT) 对骨转移的前列腺癌效果较差. 阻断TGF-β增强了Th1反应,改善了骨转移性前列腺癌 (mCRPC) 模型的存活率.

关键词:
T ((h) 1子集TGF-β阻塞抗CTLA-4的药物抗PD-1 的骨头转移抗割前列腺癌

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