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卡斯帕斯-8是细胞亡,死细胞亡和热细胞亡的分子开关

Melanie Fritsch1, Saskia D Günther1, Robin Schwarzer2

  • 1Institute for Medical Microbiology, Immunology and Hygiene (IMMIH), CECAD Research Center, University of Cologne, Cologne, Germany.

Nature
|November 22, 2019
PubMed
概括

在小鼠中,非活跃的caspase-8 (CASP8 ((C362S)) 通过诱导亡和亡导致胚胎死亡. 阻断亡意外导致后期死亡,揭示了caspase-8在预防组织损伤中的作用.

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