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胆酸代谢物控制TH17和Treg细胞的分化

Saiyu Hang1, Donggi Paik1, Lina Yao2

  • 1Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

Nature
|November 29, 2019
PubMed
概括

胆汁酸代谢物调节适应性免疫. 在小鼠中发现,特定的石化酸衍生物抑制了T助手17 (TH17) 细胞分化,并促进了调节性T (Treg) 细胞分化.

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The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
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