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Updated: Jan 2, 2026

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粉体光动力学损伤的纳米尺度图

Patricia Bondia1, Joaquim Torra1, Caterina M Tone1

  • 1Madrid Institute for Advanced Studies in Nanoscience (IMDEA Nanociencia) , C/Faraday 9 , Madrid 28049 , Spain.

Journal of the American Chemical Society
|November 30, 2019
PubMed
概括

研究人员研究了光催化剂如何与粉样聚合物结合以及光照后的效果. 这项工作通过了解光降解机制来推进粉样蛋白相关疾病的光疗策略.

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
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