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Updated: Jan 2, 2026

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在人类胚胎中确定染色质结构中的CTCF的关键作用

Xuepeng Chen1, Yuwen Ke1, Keliang Wu2

  • 1CAS Key Laboratory of Genome Sciences and Information, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.

Nature
|December 6, 2019
PubMed
概括

人类精子缺乏CTCF和拓关联域 (TAD). 在人类胚胎发育过程中建立了TAD,需要在胚胎基因组激活 (ZGA) 时表达CTCF.

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