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Updated: May 6, 2026

Transcriptome Analysis of Single Cells
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Transcriptome Analysis of Single Cells

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在单细胞分辨率下大规模复杂化学转录组学

Sanjay R Srivatsan1,2, José L McFaline-Figueroa1, Vijay Ramani1,3

  • 1Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Science (New York, N.Y.)
|December 7, 2019
PubMed
概括

我们开发了sci-Plex, 一种使用核散列的方法来分析单细胞对数千种化学化合物的转录反应. 这种方法揭示了详细的细胞反应和复合家族相似性,提高了药物查能力.

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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