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一个类似菌体核的隔间保护DNA免受CRISPR核酶的影响

Senén D Mendoza1, Eliza S Nieweglowska2, Sutharsan Govindarajan1,3

  • 1Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.

Nature
|December 11, 2019
PubMed
概括

大菌体 ΦKZ 通过构建一个类似于核的隔间来逃避细菌免疫系统,保护其DNA免受核酶的影响. 这种蛋白质屏障保护了菌体基因组,使得宿主体内的有效复制成为可能.

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