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Updated: Jan 2, 2026

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发现具有Huisgenase活动的生物分子:设计重复蛋白作为 (3 + 2) 循环添加物的生物催化剂

Iván Rivilla1, Mikel Odriozola-Gimeno1, Antonio Aires2

  • 1Department of Organic Chemistry I, Centro de Innovación en Química Avanzada (ORFEO-CINQA) , Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU) and Donostia International Physics Center (DIPC) , P° Manuel Lardizabal 3 , E-20018 Donostia/San Sebastián , Spain.

Journal of the American Chemical Society
|December 13, 2019
PubMed
概括

工程蛋白质,称为Huisgenases,催化不自然的1,3-二极反应,创建新的尼特烯. 这些蛋白质提供了对反应结果的精确控制,证明了生物催化物的新前沿.

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