为什么需要治愈艾滋病毒,在哪里需要治愈艾滋病毒,以及如何治愈艾滋病毒
Thumbi Ndung'u1,2,3, Joseph M McCune4, Steven G Deeks5
1Africa Health Research Institute, Durban, South Africa.
Nature
|December 20, 2019
概括
由于终身抗逆转录病毒治疗的局限性,开发有效的艾滋病毒治疗是全球优先事项. 扩大对撒哈拉以南非洲等地区的研究对于具有影响力的干预措施至关重要.
科学领域:
- 传染性疾病
- 病毒学
- 公共卫生
背景情况:
- 全球只有60%的HIV感染者接受抗逆转录病毒治疗.
- 目前的艾滋病毒治疗方案面临可持续性挑战.
- 艾滋病毒发病率的适度下降凸显出需要更好的干预措施.
研究的目的:
- 审查有效治愈艾滋病毒的需要和潜在策略.
- 强调开发治疗艾滋病毒的全球优先事项.
- 倡导扩大艾滋病毒治疗研究工作.
主要方法:
- 审查现有的全球艾滋病毒研究和治疗计划.
- 对生物,治疗和实施挑战的分析.
- 评估艾滋病毒干预的获取和有效性的区域差异.
主要成果:
- 终身抗逆转录病毒治疗存在复杂性和重大开支.
- 有效治愈艾滋病毒是全球卫生重点.
- 为了成功实施治愈艾滋病毒,必须应对特定地区的挑战.
结论:
- 在资源丰富的地区之外扩大艾滋病毒治疗研究是必不可少的.
- 解决生物,治疗和实施问题是有效的HIV干预的关键.
- 需要全球共同努力才能治愈艾滋病毒,
相关概念视频
Retrovirus Life Cycles
49.1K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
49.1K
Sexually Transmitted Infections
799
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
799
Curing Methods
242
Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...
242


