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相关概念视频

Direct Motor Pathways01:11

Direct Motor Pathways

4.0K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
4.0K
Hierarchy of Motor Control01:18

Hierarchy of Motor Control

5.8K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
5.8K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

6.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
6.6K
Indirect Motor Pathways01:22

Indirect Motor Pathways

2.9K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
2.9K
Muscles of the Forearm that Move the Hand and Fingers01:17

Muscles of the Forearm that Move the Hand and Fingers

2.3K
The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi...
2.3K
Generation of Action Potential in Skeletal Muscles01:24

Generation of Action Potential in Skeletal Muscles

8.1K
Every cell in the body maintains a membrane potential due to an uneven distribution of positive and negative charges across its plasma membrane. The membrane potential is measured in millivolts and quantifies the difference in charge across the membrane.
Like neurons, muscle cells are also regarded as excitable due to their capacity to change in response to stimuli, primarily due to voltage-gated ion channels embedded in their plasma membranes, which get activated by alterations in the...
8.1K

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相关实验视频

Updated: Jan 1, 2026

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
07:52

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

Published on: November 22, 2021

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在右手运动期间皮质模式生成是输入驱动的

Britton A Sauerbrei1, Jian-Zhong Guo1, Jeremy D Cohen1

  • 1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.

Nature
|December 27, 2019
PubMed
概括
此摘要是机器生成的。

运动皮质产生熟练的手臂运动, 但外在的输入, 这表明一个分布式的模式生成器为灵巧的手臂运动.

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Corticospinal Excitability Modulation During Action Observation

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相关实验视频

Last Updated: Jan 1, 2026

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
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In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

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科学领域:

  • 神经科学
  • 发动机控制
  • 系统神经科学

背景情况:

  • 运动皮质对于熟练的手臂运动至关重要,
  • 据信当地的皮层动力学在运动执行过程中塑造了这些运动模式.
  • 外部输入可能会影响运动皮质的初始状态,并可能有助于模式生成.

研究的目的:

  • 研究皮层动态和外部输入在小鼠捕捉任务中产生运动模式的不同作用.
  • 确定皮质状态和乳头输入的干扰如何影响运动的启动和执行.

主要方法:

  • 皮层状态的扰乱到异常状态和释放后运动启动的观察.
  • 塔拉木斯的非激活,以评估外部输入对皮质活动和四肢动力学的影响.
  • 在不同频率的thalamocortical轴突终端的激活.
  • 同时记录皮质和胸膜活动.

主要成果:

  • 干扰运动皮层阻止了运动的启动;在释放时,皮层要么绕过了正常的初始状态,要么无法生成达到的模式,这表明依赖输入的恢复.
  • 在所有阶段都破坏了皮质活动和四肢运动.
  • 观察到皮质活动和手臂运动的渐进性干扰,其thalamocortical轴突终端激活的频率各不相同.
  • 甲状腺活动和当前皮质状态都预测了皮质活动的后续变化.

结论:

  • 灵巧手臂运动的模式生成器不仅仅依赖于局部皮质动力学,而且分布在多个相互作用的大脑区域,
  • 外部输入,特别是来自丘脑的输入,在启动和调节运动模式中起着重要作用.
  • 运动控制包括局部皮质状态和外部驱动力之间的动态相互作用.