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Updated: Aug 5, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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纳米颗粒结合稳定和多元化β-毛针以有效地准PD-1/PD-L1β-sheet-rich接口

Woo-Jin Jeong, Jiyoon Bu, Yanxiao Han

  • 1Yonsei Frontier Lab, Department of Pharmacy , Yonsei University , Seoul 03722 , Republic of Korea.

Journal of the American Chemical Society
|January 3, 2020
PubMed
概括

这项研究引入了一种 - 树突结合物 (PDC) 来稳定β-毛,增强它们与抗癌免疫治疗中的PD-L1等具有挑战性的蛋白的结合.

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Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...