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Updated: Dec 31, 2025

A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer
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A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer

Published on: September 13, 2022

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结合Aptamer和Mitomycin C与降解剂反应链接剂导致协同增强的抗癌作用

Qiuxia Yang1, Zhengyu Deng1, Dan Wang1

  • 1Molecular Sciences and Biomedicine Laboratory (MBL), State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Collaborative Innovation Center for Chemistry and Molecular Medicine , Hunan University , Changsha 410082 , China.

Journal of the American Chemical Society
|January 8, 2020
PubMed
概括

通过向癌细胞来增强癌症治疗的Aptamer-mitomycin C结合物. 一种二硫酸结合器策略显著提高了药物的有效性,并减少了消化道癌症的副作用.

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