番茄中高度修饰的脂肪酸的病原体反应基因集群
Ju Eun Jeon1, Jung-Gun Kim2, Curt R Fischer3
1Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Cell
|January 11, 2020
概括
植物产生独特的脂肪酸来防御病原体. 研究人员在番茄中发现了一组基因,该基因负责产生抗真菌和细菌感染的化合物 - - 基因.
科学领域:
- 植物生物化学
- 分子生物学
- 化学生态学
背景情况:
- 植物在生物压力下合成复杂的脂肪酸.
- 装饰性脂肪酸在病原体防御中起作用,但它们的生物合成知之甚少.
- 一种在多种植物中发现的乙脂,具有抗真菌和抗癌特性.
研究的目的:
- 为了确定植物中丁醇的生物合成途径.
- 阐明特定基因在猎醇生产中的作用.
- 调查虫对植物防御机制的作用.
主要方法:
- 番茄 (Solanum lycopersicum) 的非向代谢和RNA测序
- 最初的生物合成步骤的异质表达.
- 转基因番茄突变体的产生用于途径分析.
主要成果:
- 在番茄中发现了一种重要的新生物合成基因集群.
- 复制实验证实了在生物合成中的作用.
- 转基因番茄系表现出改变的基醇水平和对真菌和细菌病原体的修饰性耐药性.
结论:
- 一个特定的基因集群控制了西红中基脂的生物合成.
- 丁醇生物合成有助于植物对微生物病原体的防御.
- 这项研究提供了植物脂质修饰和防御策略的关键见解.
更多相关视频
相关概念视频
Transgenic Plants
8.3K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
8.3K
Gene Regulation During Sporulation
380
Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...
380
Prokaryotic Transcriptional Activators and Repressors
25.1K
The organization of prokaryotic genes in their genome is notably different from that of eukaryotes. Prokaryotic genes are organized, such that the genes for proteins involved in the same biochemical process or function are located together in groups. This group of genes, along with their regulatory elements, are collectively known as an operon. The functional genes in an operon are transcribed together to give a single strand of mRNA known as polycistronic mRNA.
Transcription of prokaryotic...
Transcription of prokaryotic...
25.1K


