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Updated: Dec 30, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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一个抗CRISPR病毒环核酶颠覆了CRISPR类型III免疫力

Januka S Athukoralage1, Stephen A McMahon1, Changyi Zhang2,3

  • 1Biomedical Sciences Research Complex, School of Biology, University of St Andrews, St Andrews, Fife, UK.

Nature
|January 17, 2020
PubMed
概括

病毒可以通过使用一种新的酶,AcrIII-1来逃避细菌的CRISPR免疫力,该酶会降解循环四乙烯酸 (cA4) 信号分子. 这一发现揭示了一种新的病毒策略,

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