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Updated: Dec 29, 2025

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
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灵长类卵巢衰老的单细胞转录图谱

Si Wang1, Yuxuan Zheng2, Jingyi Li3

  • 1State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Brain Disorders, Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Cell
|February 1, 2020
PubMed
概括

卵巢衰老和生育能力下降与氧化损伤有关,特别是在卵细胞和粒状细胞中. 这项研究揭示了与年龄相关的生育问题的分子机制和潜在治疗点.

关键词:
年龄增长抗氧化基因颗粒细胞卵子细胞卵巢灵长类动物单细胞RNA测序

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