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Updated: Dec 29, 2025

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
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Published on: August 4, 2016

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癌症中的RNA改变的基因组基础

, Claudia Calabrese1, Natalie R Davidson2,3,4,5,6

  • 1European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.

Nature
|February 7, 2020
PubMed
概括

这项研究使用1188名捐赠者的转录组对癌症相关的基因变异进行了分类. 它将RNA变化与DNA变化联系在一起,揭示了体质拷贝数量的变化是基因表达变化的关键驱动因素.

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