损伤和微生物模式的同时发生控制了根部的局部免疫反应
Feng Zhou1, Aurélia Emonet1, Valérie Dénervaud Tendon1
1Department of Plant Molecular Biology, Biophore, UNIL-Sorge, University of Lausanne, 1015 Lausanne, Switzerland.
Cell
|February 8, 2020
概括
植物根可以通过局部细胞损伤激活不响应细胞的免疫反应. 这种损害隔离机制使植物能够在土壤中检测微生物相关的分子模式 (MAMPs).
科学领域:
- 植物免疫力
- 植物与微生物的相互作用
- 细胞生物学
背景情况:
- 识别与微生物相关的分子模式 (MAMPs) 对植物免疫至关重要.
- 但它们如何感知MAMPs仍不清楚.
研究的目的:
- 调查植物根如何感知MAMPs尽管持续的微生物暴露.
- 了解细胞损伤对植物根部免疫反应的作用.
主要方法:
- 在Arabidopsis根中分析MAMP受体表达和细胞反应.
- 使用激光切除来诱导局部细胞损伤.
- 观察受损后对有益细菌的免疫反应.
主要成果:
- 不同化的外根细胞表达低水平的模式识别受体 (PRR) 并对MAMP无反应.
- 邻近的细胞损伤可以提高PRR的表达,从而诱导邻近的细胞对MAMP的反应.
- 局部损伤会触发对有益细菌的免疫反应,这种反应可以被受体过度表达所覆盖.
结论:
- 细胞损伤起到关门机制的作用,使其他不响应的根细胞能够感知MAMP.
- 在微生物丰富的土壤环境中,这种损害防护策略使植物能够有效地管理免疫反应.
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