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孤立的缩性高血压的决定因素
S V Wilking1, A Belanger, W B Kannel
1Geriatrics Section, Evans Memorial Department of Clinical Research, University Hospital, Boston University Medical Center, MA 02118.
JAMA
|December 16, 1988
概括
隔离性缩性高血压 (ISH) 在老年人中很常见. 关键的危险因素包括年龄的增长,性别,血压水平和女性肥胖.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 流行病学 流行病学
背景情况:
- 隔离性缩性高血压 (ISH) 是一种普遍存在的高血压形式,特别是在老年人中.
- ISH被定义为静缩血压 (SBP) ≥160毫米升,静缩血压 (DBP) <95毫米升.
研究的目的:
- 为了确定ISH的发病率和流行率.
- 评估弗雷明汉心脏研究队列中与ISH相关的潜在风险因素.
主要方法:
- 纵向研究分析了16次两年一次的检查数据.
- 风险人群包括1687名男性和1992名女性,在基线时SBP<160毫米.
- 评估的因素包括年龄,性别,血压成分,体重,胆固醇,尿酸,吸烟,心率,葡萄糖不耐受和血红素.
主要成果:
- 在男性中,ISH的患病率为14.4%,在女性中为22.8%.
- 累计发病率为男性的418/1000和女性的533/1000.
- 确定的重大风险因素包括年龄,性别,血压成分和相对体重增加 (女性).
结论:
- 在老年人群中,ISH是一种非常普遍的疾病.
- ISH的主要决定因素包括晚年,性别,高血压和肥胖 (尤其是女性).
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