辛的食物和胃. 通过视频内镜进行评估
D Y Graham1, J L Smith, A R Opekun
1Digestive Disease Section, Veterans Administration Medical Center, Houston, TX 77030.
在一项研究中,菜和披萨等辛食品并没有造成显著的胃内膜损伤. 然而,阿司匹林导致严重的胃侵蚀,表明它对胃粘膜构成更大的风险.
科学领域:
- 胃肠病学 胃肠病学
- 消化系统健康 消化系统健康
- 内镜检查是指内镜检查.
背景情况:
- 辛食物对胃粘膜的影响仍在争论中.
- 以前的研究已经产生了相互矛盾的结果,关于辛食物对胃内膜的影响.
研究的目的:
- 用视频内镜检查辛食物对胃和十二指肠粘膜的影响.
- 为了比较辛食物和阿司匹林造成的粘膜损伤.
主要方法:
- 一个随机的交叉试验,涉及12名健康受试者.
- 四个测试餐被管理:平淡的控制,平淡的阿司匹林,辛的墨西哥菜,和胡卜素披萨.
- 内镜在基线和饭后12小时进行,使用修改后的兰扎尺度评分损伤.
主要成果:
- 阿司匹林显著增加了胃侵蚀 (中位数C,严重损伤).
- 辛的食物 (墨西哥菜,披萨) 和平淡的食物显示粘膜损伤很小或没有 (中位数为0).
- 对胃粘膜直接施加哈拉佩诺胡也没有显示任何损伤.
结论:
- 在健康个体中,摄入高调味料的食物不会引起显著的内镜检测到的胃肠粘膜损伤.
- 与辛食物相比,阿司匹林对胃粘膜损伤的风险要大得多.
- 进一步的研究可能会探索个体敏感性或慢性影响.
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