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Updated: Dec 27, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells

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通过共价对接发现素向eIF4E抑制剂

Xiaobo Wan, Tangpo Yang, Adolfo Cuesta

    Journal of the American Chemical Society
    |February 28, 2020
    PubMed
    概括

    研究人员开发了针对真核转化启动因子4E (eIF4E) 的新型共价抑制剂,重点关注氨酸残留物. 通过抑制细胞生长和转移的关键蛋白质,

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