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相关概念视频

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.0K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
11.0K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

11.9K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
11.9K
Olfaction01:25

Olfaction

47.9K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
47.9K
Introduction to Special Senses01:26

Introduction to Special Senses

7.2K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
7.2K
Introduction to Sensory Receptors01:31

Introduction to Sensory Receptors

7.4K
Sensory receptors are vital in our ability to perceive and interpret the world. Sensory receptors are specialized cells in the peripheral nervous system that respond to various stimuli and enable one to experience different sensations. Based on specific criteria, sensory receptors are classified into distinct types.
The first classification criterion is based on cell type, position, and function. Some receptor cells are neurons with free nerve endings, where their dendrites are embedded in the...
7.4K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

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Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
624

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相关实验视频

Updated: Dec 27, 2025

Multi-unit Recording Methods to Characterize Neural Activity in the Locust Schistocerca Americana Olfactory Circuits
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Multi-unit Recording Methods to Characterize Neural Activity in the Locust Schistocerca Americana Olfactory Circuits

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嗅觉受体和电路进化促进宿主专业化.

Thomas O Auer1, Mohammed A Khallaf2, Ana F Silbering3

  • 1Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. Thomas.Auer@unil.ch.

Nature
|March 6, 2020
PubMed
概括

研究了果 (Drosophila sechellia) 行为的进化,特别是寻找宿主. 研究人员确定了基因和神经变化,这些变化是对果的吸引力背后的原因,揭示了对物种化和神经系统进化的洞察力.

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Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
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Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

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Live-cell Measurement of Odorant Receptor Activation Using a Real-time cAMP Assay
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Live-cell Measurement of Odorant Receptor Activation Using a Real-time cAMP Assay

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相关实验视频

Last Updated: Dec 27, 2025

Multi-unit Recording Methods to Characterize Neural Activity in the Locust Schistocerca Americana Olfactory Circuits
12:13

Multi-unit Recording Methods to Characterize Neural Activity in the Locust Schistocerca Americana Olfactory Circuits

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Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
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Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

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科学领域:

  • 神经遗传学 神经遗传学
  • 进化生物学 进化生物学
  • 动物行为 动物行为

背景情况:

  • 动物行为进化的遗传基础是不太了解的.
  • 很少有研究证明了物种之间的行为差异的遗传基础.

研究的目的:

  • 为了研究Drosophila sechellia,一种专注于果的物种行为分歧的神经遗传基础.
  • 确定驱动特定物种寻找宿主行为的分子和神经机制.

主要方法:

  • 利用成像来识别Drosophila sechellia中的嗅觉通路.
  • 在嗅觉受体上进行突变分析和跨种类的等位基因转移实验.
  • 在Drosophila sechellia的大脑中进行了电路跟踪.

主要成果:

  • 确定了特定的嗅觉受体,对长距离和短距离对果的吸引力至关重要.
  • 证明了嗅觉受体的调整是特定物种寻找宿主的关键.
  • 发现神经适应,包括感官聚合和改变的投影模式,伴随着受体变化.

结论:

  • 揭示了分子,生理和解剖学特征的积累,导致行为分歧.
  • 确立了Drosophila sechellia作为研究物种化和神经系统进化的模型系统.