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Updated: Dec 26, 2025

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以依赖IL-6的方式促进大脑修复

Emily F Willis1, Kelli P A MacDonald2, Quan H Nguyen3

  • 1School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.

Cell
|March 7, 2020
PubMed
概括

在创伤性脑损伤 (TBI) 后, 操纵小质细胞 (大脑中的免疫细胞) 可以促进恢复. 通过利用IL-6转信号来增强神经发生和认知功能.

关键词:
A1星球细胞积极避开地点补充学习和记忆巨细胞神经干细胞/原生细胞神经炎症神经创伤复苏的小质细胞空间转录学

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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