中东呼吸系统综合征
Ziad A Memish1, Stanley Perlman2, Maria D Van Kerkhove3
1College of Medicine, Alfaisal University, Riyadh, Saudi Arabia; Research Center, King Saud Medical City Ministry of Health, Riyadh, Saudi Arabia; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Lancet (London, England)
|March 8, 2020
概括
中东呼吸综合征冠状病毒 (MERS-CoV) 导致严重的疾病和高死亡率. 持续的监测和研究对于控制这一优先病原体和预防未来的疫情至关重要.
科学领域:
- 传染性疾病
- 公共卫生
- 病毒学
背景情况:
- 中东呼吸综合征冠状病毒 (MERS-CoV) 是一种致命的动物病原体,于2012年出现.
- 在全球范围内,MERS-CoV 继续引起零星病例,社区群体和医院疫情.
- 世界卫生组织 (WHO) 认定MERS-CoV是重点病原体,因为它具有严重的疾病,高死亡率和流行病潜力.
研究的目的:
- 提供有关MERS-CoV知识的最新概述.
- 突出目前MERS流行病学,病毒学,传播,发病,诊断,临床特征和管理方面的观点.
- 确定改善预防和控制的研究重点.
主要方法:
- 本研讨会综合了报告的MERS-CoV病例和疫情的当前知识.
- 它审查了流行病学,临床特征和管理策略的数据.
- 它还讨论了正在进行的治疗和疫苗开发研究.
主要成果:
- 从2012年4月到2019年12月,全球27个国家报告了2499例MERS-CoV确诊病例和858例死亡病例 (死亡率为34.3%).
- 沙特阿拉伯报告了大多数病例 (2106) 和死亡 (780).
- 包括在韩国 (2015) 发生了重大人与人传染疫情.
结论:
- 尽管如此,MERS-CoV 仍然是一个严重的全球健康威胁,需要持续保持警.
- 迫切需要有效的医疗对策,包括治疗和疫苗.
- 为了更好地了解,管理和预防MERS-CoV,进一步的研究至关重要.
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