减少动脉和毛细血管之间的过渡段的超肌化,防止自发性脑内出血

Julien Ratelade1, Nicholas R Klug2, Damiano Lombardi3

  • 1Institute of Psychiatry and Neurosciences of Paris (IPNP), Inserm U1266, University of Paris, France (J.R., M.K.S.C.A., V.D-D., A.J.).

Circulation
|March 19, 2020
PubMed
概括

深度脑内出血 (ICH) 涉及两种血管缺陷:过渡段肌肉化和光滑肌肉细胞损失. 这种由Notch3驱动的双重缺陷增加了压力并促进了断裂,

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