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Updated: Jul 13, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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Published on: February 28, 2019

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基因工程T细胞活动的定量控制通过向配体对通用免疫受体的共价连接

Nicholas G Minutolo, Prannda Sharma, Mathilde Poussin

    Journal of the American Chemical Society
    |March 20, 2020
    PubMed
    概括

    一种全新的免疫受体,SpyCatcher, 能够进行适应性T细胞治疗. 这种方法通过精确控制T细胞向和对抗多个瘤抗原,克服了癌症治疗的挑战.

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