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Updated: Dec 25, 2025

Tyramide Signal Amplification for the Immunofluorescent Staining of ZBP1-Dependent Phosphorylation of RIPK3 and MLKL After HSV-1 Infection in Human Cells
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流感病毒Z-RNA诱导ZBP1介导的死亡

Ting Zhang1, Chaoran Yin1, David F Boyd2

  • 1Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, USA.

Cell
|March 24, 2020
PubMed
概括

流感A病毒的复制会产生Z-RNAs,在细胞核中激活ZBP1,从而启动亡. 这种途径增加了中性粒细胞的激活和疾病的严重程度,突出了流感治疗的新目标.

关键词:
其他类型在RIPKZ-RNA 的使用一个ZBP细胞亡卡斯帕斯-8dsRNA 的时间流感 的尸体死亡

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