运动前皮层的手旋区域以组成的方式代表整个身体
Francis R Willett1, Darrel R Deo2, Donald T Avansino3
1Department of Neurosurgery, Stanford University, Stanford, CA, USA; Department of Electrical Engineering, Stanford University, Stanford, CA, USA; Howard Hughes Medical Institute at Stanford University, Stanford, CA, USA.
Cell
|March 30, 2020
概括
研究人员在前运动皮质中发现了一种"构成性"的神经代码, 这项发现有助于人们更好地了解四肢患者的运动控制和脑电脑接口.
科学领域:
- 神经科学
- 发动机控制
- 大脑与计算机的接口
背景情况:
- 单个神经元水平上的运动同胞组织仍然不清楚.
- 运动皮层区域的身体部位之间的相互作用尚不清楚.
研究的目的:
- 在前运动皮层的手旋区域研究面部,头部,手臂和腿部运动的神经表现.
- 阐明四肢患者运动控制的神经编码原理.
主要方法:
- 在前运动皮质 (前中心环) 的手旋区域使用多单元记录.
- 在四肢患者的脸部,头部,手臂和腿部运动中研究神经表现.
主要成果:
- 与传统模型相反, 发现了所有被研究的运动的强烈代表性.
- 找到了连接四个肢体的部分"组成"神经代码.
- 该代码包括一个肢体编码组件和一个运动编码组件,用于跨肢体的类似运动.
结论:
- 组合编码可能有助于跨肢体的技能转移.
- 为了解运动系统如何构建运动提供了一个新的框架.
- 能够为四肢患者开发全身皮层内脑计算机接口.
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