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Updated: Dec 25, 2025

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通过结构向性联体对瘤性微RNA 17-92 集群进行向性降解

Xiaohui Liu1, Hafeez S Haniff1, Jessica L Childs-Disney1

  • 1Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|April 3, 2020
PubMed
概括

研究人员开发了新的RNA向化合物来抑制microRNA-17-92集群, 作为癌症等疾病的关键参与者. 这些化合物在临床前模型中选择性地降低了与疾病相关的microRNA水平并挽救了表型.

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