检查孕妇的细菌性阴道炎以防止早产:美国预防服务工作组建议声明
, Douglas K Owens1,2, Karina W Davidson3
1Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
JAMA
|April 8, 2020
概括
在没有高风险的孕妇中查细菌性阴道炎没有被证明的好处. 证据不足以确定风险较高的人的益处与危害.
科学领域:
- 产科和妇科
- 传染性疾病
- 预防医学
背景情况:
- 细菌性阴道炎 (BV) 破坏下生殖道的微生物组,影响孕妇.
- 美国的患病率在5.8%至19.3%之间,某些人口群体的患病率更高.
- 怀孕中的VB与早产,流产和低出生体重等不良结果有关.
研究的目的:
- 更新2008年关于对无症状孕妇进行 BV 查的建议.
- 评估查准确度的证据以及预防早产的 BV 查和治疗的益处/危害.
主要方法:
- 系统审查证据由USPSTF委托.
- 侧重于查测试的准确性和查和治疗的临床结果.
- 包括无症状的孕妇,对早产风险较高的人进行分组分析.
主要成果:
- 适度的确定性,在没有早产风险的无症状孕妇的查没有净益处.
- 对于早产风险较高的人来说, 有矛盾且不足的证据.
结论:
- USPSTF建议在没有早产风险的孕妇中不进行 BV 查 (D 建议).
- 证据不足以评估预产风险增加的孕妇查的益处危害平衡 (I声明).
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