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一个保存的树突细胞调节程序限制了抗瘤免疫力

Barbara Maier1,2,3, Andrew M Leader1,2,3, Steven T Chen1,2,3

  • 1The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature
|April 10, 2020
PubMed
概括

研究人员发现一种新型树突细胞 (DC) 阻碍抗癌免疫疗法. 在这些成熟的免疫调节分子 (mregDCs) 中阻断特定的信号通路恢复了抗瘤免疫力并减少了瘤生长.

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