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Updated: Dec 23, 2025

A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl
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来自细胞毒性淋巴细胞的Granzyme A分裂GSDMB以触发细胞

Zhiwei Zhou1,2, Huabin He3,2, Kun Wang2

  • 1Research Unit of Pyroptosis and Immunity, Chinese Academy of Medical Sciences and National Institute of Biological Sciences, Beijing, Beijing 102206, China.

Science (New York, N.Y.)
|April 18, 2020
PubMed
概括

细胞毒性淋巴细胞通过烧灭,一个被编程的细胞死亡杀死GSDMB阳性细胞. 淋巴细胞大酶A分裂GSDMB,启动这种炎症性细胞死亡并促进抗瘤免疫力.

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