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在非人类灵长类动物模型中,对COVID-19,MERS和SARS的比较病原性

Barry Rockx1, Thijs Kuiken2, Sander Herfst2

  • 1Department of Viroscience, Erasmus University Medical Center, Rotterdam, Netherlands. b.rockx@erasmusmc.nl b.haagmans@erasmusmc.nl.

Science (New York, N.Y.)
|April 19, 2020
PubMed
概括

研究人员将的SARS-CoV-2病变与其他冠状病毒进行了比较. SARS-CoV-2 引起了类似COVID-19的疾病,为研究病毒感染和开发治疗提供了新的模式.

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Single Nucleotide Polymorphisms-SNPs01:05

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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