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Updated: Dec 23, 2025

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使用可光切换的阿佐皮拉进行CRAC通道的光学控制

Xingye Yang1, Guolin Ma2, Sisi Zheng3

  • 1Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, School of Pharmacy, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.

Journal of the American Chemical Society
|April 25, 2020
PubMed
概括

研究人员开发了新的光控制抑制剂 (piCRACs) 来阻断释放激活通道 (CRAC). 这些piCRAC有效地减少了斑马鱼的Stormorken综合征症状,证明了CRAC通道疾病的新治疗方法.

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相关概念视频

Channel Rhodopsins01:11

Channel Rhodopsins

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Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
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