使用感官运动解复神经接口恢复触觉
Patrick D Ganzer1, Samuel C Colachis1, Michael A Schwemmer2
1Medical Devices and Neuromodulation, Battelle Memorial Institute, 505 King Avenue, Columbus, OH 43201, USA.
Cell
|April 25, 2020
概括
这项研究表明,脑电脑接口 (BCI) 可以恢复脊髓损伤患者的运动和触觉. 通过BCI解码神经信号使的肌肉复苏并提供感官反.
科学领域:
- 神经科学
- 生物医学工程
- 康复医学
背景情况:
- 脊髓损伤 (SCI) 通常会导致和失去感觉.
- 脑电脑接口 (BCI) 在SCI后恢复运动功能方面表现有前途.
- 恢复触觉对于有效的运动控制和功能恢复至关重要.
研究的目的:
- 通过BCI在完全SCI的参与者身上研究运动功能和触觉的同时恢复.
- 探索关闭循环感官反的残留神经信号的解码.
- 通过将运动复苏与触觉感知相结合来增强感官运动功能.
主要方法:
- 在临床上完全脊髓损伤的人体参与者中使用脑电脑接口 (BCI).
- 从主要运动皮层 (M1) 与运动意图信号一起去复杂的残留感知触觉信号.
- 开发了一个闭环系统用于皮质内传感反,并从M1解码了 afferent握力强度水平.
主要成果:
- 闭环BCI系统几乎完全恢复了参与者检测物体触摸的能力.
- 观察到各种感觉运动功能的显著改善.
- 通过解码触摸信号来调节.
结论:
- 从大脑皮层传递的神经信号可以被解码并转化为意识感知.
- 在SCI之后,BCI可以同时恢复运动功能和触觉.
- 这种方法通过将感官反整合到运动控制中, 显著增加功能恢复.
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