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针对SARS-CoV-2突发现场的特定葡萄糖分析

Yasunori Watanabe1,2,3, Joel D Allen1, Daniel Wrapp4

  • 1School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK.

Science (New York, N.Y.)
|May 6, 2020
PubMed
概括

研究人员分析了SARS-CoV-2尖端蛋白的甘氨酸,发现它们与典型的人类细胞处理不同. 这一发现为开发有效的COVID-19疫苗和了解病毒行为提供了洞察力.

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Protein Glycosylation01:25

Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
Glycosylation occurs in...
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