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Updated: Dec 22, 2025

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通过可逆和不可逆共价PROTAC有效的向降解

Ronen Gabizon1, Amit Shraga1, Paul Gehrtz1

  • 1Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot 7610001, Israel.

Journal of the American Chemical Society
|May 6, 2020
PubMed
概括

可逆共价PROTAC为向蛋白质降解提供了一种有效和选择性的方法,克服了传统方法的局限性. 这项研究表明它们在降解Bruton

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