安第斯山脉深层人口历史的古遗传学重建
Nathan Nakatsuka1, Iosif Lazaridis2, Chiara Barbieri3
1Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA.
Cell
|May 11, 2020
概括
古安第斯遗传历史显示,在公元前5800年,人口结构形成. 尽管混合程度有限,但莫切,瓦里,蒂瓦纳库和印加社会存在宇宙主义,并观察到远程移动.
科学领域:
- 古代DNA分析
- 种群遗传学
- 安第斯地区的考古学
背景情况:
- 关于中部和中南部安第斯山脉的人口历史的问题仍未得到答案.
- 莫切,瓦里,蒂瓦纳库和印加等大规模社会对遗传结构的影响尚未完全理解.
研究的目的:
- 使用全基因组数据调查中部和中南部安第斯山脉的人口历史.
- 专注于该地区国家社会兴衰的遗传影响.
主要方法:
- 收集来自89个个体的全基因组数据.
- 样品的年代约为9000至500年前 (BP).
- 基因结构,基因流动,混合和移动模式的分析.
主要成果:
- 安第斯目前的遗传结构始于公元前5800年左右.
- 双向基因流发生在北部和南部高地之间,以及高地和海岸之间.
- 在2000年至500年前的邻近群体中检测到最小的混合物,但在蒂瓦纳库和印加政体中存在宇宙主义.
- 发现了连接安第斯山脉到阿根廷和西北安第斯山脉到亚马逊盆地的远程移动的证据.
结论:
- 古老的遗传数据揭示了安第斯人口结构的形成和历史基因流动.
- 国际化和远程移动性是某些时期和地区的特点,尤其是在主要的政治体内.
- 这项研究提供了对安第斯大规模社会形成的复杂人口流程的见解.
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