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一对非竞争性的人类中和抗体阻断COVID-19病毒与其受体ACE2结合

Yan Wu1,2, Feiran Wang3,4, Chenguang Shen3,5

  • 1Department of Pathogen Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. wuy@biols.ac.cn gaofeng@tib.cas.cn gaof@im.ac.cn liulei3322@aliyun.com.

Science (New York, N.Y.)
|May 15, 2020
PubMed
概括

分离了四种人类单克隆抗体,其中B38和H4阻断了SARS-CoV-2尖端蛋白与ACE2的结合. 这些中和抗体显示出COVID-19治疗方法和疫苗设计的前景.

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