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Updated: Dec 21, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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聚基合成的化学信息指导工程

Amin Zargar1,2,3, Ravi Lal1,2, Luis Valencia1,2

  • 1Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.

Journal of the American Chemical Society
|May 16, 2020
PubMed
概括

化学信息学通过指导还原循环 (RL) 交换来帮助聚基合成酶 (PKS) 工程. 这一战略成功地产生了高度的短链脂肪酸和三酸乳,从而创造了新的化学产品.

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