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Updated: Dec 20, 2025

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复制SARS-CoV-2聚合酶的结构

Hauke S Hillen1, Goran Kokic1, Lucas Farnung1

  • 1Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

Nature
|May 22, 2020
PubMed
概括

我们确定了SARS-CoV-2依赖RNA聚合酶 (RdRp) 复合物的冷电子显微镜结构. 这种结构揭示了酶如何复制病毒基因组,并提供了对抗病毒药物机制的见解.

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