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Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
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基和基C3) -H键的酶性初级氨基化

Zhi-Jun Jia1, Shilong Gao1, Frances H Arnold1

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 210-41, Pasadena, California 91125, United States.

Journal of the American Chemical Society
|May 27, 2020
PubMed
概括

研究人员开发了用于直接C(sp3) -H键氨基化的新型酶,从基胺衍生物中产生初级氨基. 这种生物催化方法为合成有价值的氨基化合物提供了高选择性和效率.

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