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Updated: Dec 20, 2025

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
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通过量子力学/分子力学自由能量模拟探讨对关氨酸-丁氨酸错配的环境影响

Pengfei Li1, Atul Rangadurai2, Hashim M Al-Hashimi2

  • 1Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520, United States.

Journal of the American Chemical Society
|May 28, 2020
PubMed
概括

基因组分离会产生错配,可能导致突变. 这项研究通过计算检查了不同环境中的关氨酸-丁氨酸 (G-T) 错配对的分离,揭示了对G-T错配对稳定性和反应机制的重大环境影响.

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