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确保在小鼠伪自体区域中形成 meiotic DNA 断裂

Laurent Acquaviva1, Michiel Boekhout2,3, Mehmet E Karasu2,4,5

  • 1Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. acquavil@mskcc.org.

Nature
|May 29, 2020
PubMed
概括

研究人员确定了控制性染色体伪自体区域 (PAR) 重组的因素. 这一区域对于雄性半球变异至关重要,并且需要特定的蛋白质来形成双链断裂 (DSB).

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