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Updated: Apr 7, 2026

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
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Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

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转基因小鼠中的SARS-CoV-2病原体表达人体血管酶转化酶2

Ren-Di Jiang1, Mei-Qin Liu1, Ying Chen1

  • 1CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.

Cell
|June 10, 2020
PubMed
概括

一种新的SARS-CoV-2 hACE2转基因小鼠模型模仿了COVID-19间歇性肺炎. 这种模型对于对SARS-CoV-2感染的疫苗和治疗方法的测试有价值.

关键词:
美国冠状病毒人类ACE2转基因小鼠肺炎

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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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