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老化CAR T细胞可以逆转老化相关的病态

Corina Amor1,2, Judith Feucht3,4, Josef Leibold2

  • 1Louis V. Gerstner Jr Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|June 20, 2020
PubMed
概括

化抗原受体 (CAR) 的T细胞向泌尿酸酶类型的血激活受体 (uPAR) 有效地消除衰老的细胞. 这种老化方法显示了与年龄相关的疾病的治疗潜力,并在临床前模型中改善了生存率.

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