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Updated: Dec 18, 2025

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
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β-arrestin与formoterol结合的β1-adrenoceptor的分子基础

Yang Lee1, Tony Warne1, Rony Nehmé1,2

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|June 20, 2020
PubMed
概括

了解β1-上腺体受体 (β1AR) 信号中的偏向激应是药物开发的关键. 研究人员阐明了β-arrestin 1 (βarr1) 与β1AR的Gs蛋白合的独特结构基础.

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