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相关概念视频

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
261
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
223
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
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Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
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感染性内心炎在链球菌血流感染中的患病率取决于链球菌物种

Sandra Chamat-Hedemand1, Anders Dahl2, Lauge Østergaard3

  • 1Department of Cardiology, Zealand University Hospital, Roskilde, Denmark (S.C.-H., N.E.B.).

Circulation
|June 26, 2020
PubMed
概括

感染性内心炎 (IE) 的风险在血流链球菌感染 (BSI) 之间有显著差异. 某些物种,如突变性菌和球菌的IE流行率和风险要高得多.

关键词:
细菌性疾病感染性内心炎链球菌感染链球菌

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科学领域:

  • 传染性疾病
  • 心脏病学
  • 微生物学

背景情况:

  • 链球菌是感染性内心炎的常见原因.
  • 不同导致血流感染 (BSI) 的链球菌种的IE特异性流行率在很大程度上是未知的.
  • 对于IE的风险分层和管理来说,了解物种水平的流行率至关重要.

研究的目的:

  • 确定各种链球菌种引起的脑脊髓炎患者的发病率.
  • 确定与IE风险较高相关的特定链球菌种.

主要方法:

  • 在丹麦首都地区 (2008年至2017年) 进行的一项回顾性研究.
  • 将患者数据与全国登记处进行交叉链接,以确定同时发生的IE住院情况.
  • 通过多变量逻辑回归分析,根据已知的风险因素进行调整,以评估每种链球菌的IE风险.

主要成果:

  • 总体IE患病率在6506名链球菌性脊髓炎患者中为7. 1%.
  • 肺炎链球菌和肺炎链球菌的IE患病率最低 (分别为1. 2%和1. 9%).
  • 杆菌突变 (47. 9%),杆菌高尔多尼 (44. 2%),血球杆菌 (34. 6%),胆杆菌 (30. 2%) 和耳杆菌 (19. 4%) 的IE流行率最高.

结论:

  • 感染性内心炎在链球性BSI中的患病率高度依赖于物种.
  • 链球菌,S. gordonii,S. sanguinis,S. gallolyticus和S. mitis/ oralis与显著更高的IE风险相关.
  • 这些发现突显出需要对链球菌的BSI患者进行特定物种的风险评估.