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IL-18BP是一种分泌的免疫检查点,也是IL-18免疫治疗的障碍

Ting Zhou1, William Damsky2, Orr-El Weizman1

  • 1Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.

Nature
|June 26, 2020
PubMed
概括

通过抵抗IL-18结合蛋白 (IL-18BP) 的抑制来克服瘤的抗性. 这种新疗法增强了抗瘤免疫力和T细胞功能,

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