相关实验视频

Updated: Dec 16, 2025

Assessing Microglial Phagocytosis of Myelin Debris in vitro Under Repeated Magnetic Stimulation
08:34

Assessing Microglial Phagocytosis of Myelin Debris in vitro Under Repeated Magnetic Stimulation

Published on: June 17, 2025

788

细胞外基质的微重塑促进了突触的可塑性

Phi T Nguyen1, Leah C Dorman2, Simon Pan2

  • 1Department of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Cell
|July 3, 2020
PubMed
概括

神经元释放介质蛋白-33 (IL-33) 来指导重塑记忆中的突触. 这种IL-33通路对学习和记忆至关重要,随着年龄的增长而下降,但在IL-33时可以恢复.

关键词:
微质, 海马, 细胞外基质, 衰老, 记忆, 树突重塑, 介质素-33

更多相关视频

Immunofluorescence Staining Using IBA1 and TMEM119 for Microglial Density, Morphology and Peripheral Myeloid Cell Infiltration Analysis in Mouse Brain10:40

Immunofluorescence Staining Using IBA1 and TMEM119 for Microglial Density, Morphology and Peripheral Myeloid Cell Infiltration Analysis in Mouse Brain

Published on: October 27, 2019

34.3K
An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons07:38

An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons

Published on: June 8, 2014

18.9K

相关概念视频

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
1.3K
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.4K